Article
Investigation of genetic polymorphisms and smoking in a bladder cancer case-control study in Argentina.
Cancer letters - 10 Aug 2004
Moore Lee E, Wiencke John K, Bates Michael N, Zheng Shichun, Rey Omar A, Smith Allan H
Abstract excerpt
We investigated the role of glutathione S-transferase (GST) enzymes (M1, T1), methylenetetrahydrofolate (MTHFR) 677 and 1298, and the NAD(P)H:quinone oxidoreductase (NQO1) polymorphisms in a population-based bladder cancer case-control study in Argentina. Buccal cell DNA was obtained from 106 cases and 109 controls. The strongest evidence was for an interaction between NQO1 genotype and smoking. For ever smoking...
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