Article
Genetic polymorphisms in NQO1 and SOD2: interactions with smoking, schistosoma infection, and bladder cancer risk in Egypt.
Urologic oncology - 1 Jan 2014
Goerlitz David, Amr Sania, Dash Chiranjeev, Saleh Doa'a A, El Daly Mai, Abdel-Hamid Mohamed, El Kafrawy Sherif, Hifnawy Tamer, Ezzat Sameera, Abdel-Aziz Mohamed A, Khaled Hussein, Zheng Yun-Ling, Mikhail Nabiel, Loffredo Christopher A
Abstract excerpt
BACKGROUND: Bladder cancer is the most prevalent form of cancer in men among Egyptians, for whom tobacco smoke exposure and Schistosoma haematobium (SH) infection are the major risk factors. We hypothesized that functional polymorphisms in NAD(P)H: quinone oxidoreductase 1 (NQO1) and superoxide dismutase 2 (SOD2), modulators of the effects of reactive oxidative species, can influence an individual's...
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