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Article

Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Jun 2004

Grimm Christian, Wenzel Andreas, Stanescu Dinu, Samardzija Marijana, Hotop Svenja, Groszer Mathias, Naash Muna, Gassmann Max, Remé Charlotte

Abstract excerpt

Elevation of erythropoietin (Epo) concentrations by hypoxic preconditioning or application of recombinant human Epo (huEpo) protects the mouse retina against light-induced degeneration by inhibiting photoreceptor cell apoptosis. Because photoreceptor apoptosis is also the common path to cell loss in retinal dystrophies such as retinitis pigmentosa (RP), we tested whether high levels of huEpo would reduce...

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Identifiers

PMID: 15215287
DOI: 10.1523/JNEUROSCI.1288-04.2004
PMCID: PMC2929919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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