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Article

Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity.

The Journal of biological chemistry - 27 Aug 2004

Guo Rong-Jun, Huang Edward, Ezaki Toshihiko, Patel Neesha, Sinclair Kristen, Wu Jinling, Klein Peter, Suh Eun-Ran, Lynch John P

Abstract excerpt

The cessation of proliferation and the induction of differentiation are highly coordinated processes that occur continuously in the intestinal crypts. The homeodomain transcription factors Cdx1 and Cdx2 regulate intestine-specific gene expression and enterocyte differentiation. Their roles in reg...

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PMID: 15215241
DOI: 10.1074/jbc.M405213200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15215241-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity.PMID 15215241Read ↗

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