Article
The galU Gene of Pseudomonas aeruginosa is required for corneal infection and efficient systemic spread following pneumonia but not for infection confined to the lung.
Infection and immunity - 1 Jul 2004
Priebe Gregory P, Dean Charles R, Zaidi Tanweer, Meluleni Gloria J, Coleman Fadie T, Coutinho Yamara S, Noto Michael J, Urban Teresa A, Pier Gerald B, Goldberg Joanna B
Abstract excerpt
Acute pneumonias and corneal infections due to Pseudomonas aeruginosa are typically caused by lipopolysaccharide (LPS)-smooth strains. In cystic fibrosis patients, however, LPS-rough strains of P. aeruginosa, which lack O antigen, can survive in the lung and cause chronic infection. It is not cle...
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