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Article

Virulence properties of Pseudomonas aeruginosa lacking the extreme-stress sigma factor AlgU (sigmaE).

Infection and immunity - 1 Jul 1996

Yu H, Boucher J C, Hibler N S, Deretic V

Abstract excerpt

A discerning feature of Pseudomonas aeruginosa strains causing chronic endobronchial infections in cystic fibrosis is their conversion into the mucoid, exopolysaccharide alginate-overproducing phenotype. This morphologically prominent change is caused by mutations which upregulate AlgU (sigma(E)), a novel extreme-stress sigma factor with functional equivalents in gram-negative organisms. In this work, we...

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Identifiers

PMID: 8698507
DOI: 10.1128/iai.64.7.2774-2781.1996
PMCID: PMC174138

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Virulence properties of Pseudomonas aeruginosa lacking the extreme-stress sigma factor AlgU (sigmaE).PMID 8698507Read ↗

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