Article
Identifying families with likely genetic protective factors against Alzheimer disease.
American journal of human genetics - 1 Mar 1999
Silverman J M, Smith C J, Marin D B, Birstein S, Mare M, Mohs R C, Davis K L
Abstract excerpt
Elderly individuals who lived beyond the age of 90 years without dementia were hypothesized to have increased concentrations of genetic protective factors against Alzheimer disease (AD), conferring a reduced liability for this disease relative to less-aged nondemented elderly. However, testing this hypothesis is complicated by having to distinguish such a group from those who may lack genetic risk factors for AD,...
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