Article
Has familial aggregation in Alzheimer's disease been overestimated?
International journal of geriatric psychiatry - 1 Jul 2000
Silverman J M, Smith C M, Marin D B, Schmeidler J, Birstein S, Lantz M, Davis K L, Mohs R C
Abstract excerpt
Studies of the familial aggregation of Alzheimer's disease have primarily used samples ascertained from tertiary care clinics which may not be representative of many AD patients, for example those residing at geriatric nursing homes. Survival analysis was used to investigate whether estimates of familial aggregation of AD based on a clinic-based AD proband (C-AD) sample (probands: N=544; first degree relatives;...
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