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Article

Association of estrogen receptor alpha gene polymorphisms with neurofibrillary tangles.

Dementia and geriatric cognitive disorders - 1 Jan 2004

Kazama Hirohito, Ruberu Nyoka N, Murayama Shigeo, Saito Yuko, Nakahara Ken-Ichi, Kanemaru Kazutomi, Nagura Hiroshi, Arai Tomio, Sawabe Motoji, Yamanouchi Hiroshi, Orimo Hajime, Hosoi Takayuki

Abstract excerpt

Estrogen receptor alpha (ERalpha) may be implicated in the pathogenesis of Alzheimer's disease (AD). The aim of this study was to clarify the association between ERalpha gene polymorphisms and AD-related pathologic changes. The staging of neurofibrillary tangles (NFT) and senile plaques (SP) was...

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Source

Identifiers

PMID: 15211069
DOI: 10.1159/000079194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15211069-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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