Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Probing the world of cytochrome P450 enzymes.

Molecular interventions - 1 Jun 2004

Frye Reginald F

Abstract excerpt

Variability in drug response can be attributed in part to variability in the activity of drug-metabolizing enzymes. One of the most important drugmetabolizing enzyme systems in humans is the cytochrome P450 (CYP) enzyme family, which is responsible for the oxidative metabolism of numerous endogen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cytochrome P-450 Enzyme System
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isoenzymes

Share to Multigene Family

Share to Oxidation-Reduction

Share to Substrate Specificity

Share to Xenobiotics

Source

Identifiers

PMID: 15210869
DOI: 10.1124/mi.4.3.5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15210869-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Probing the world of cytochrome P450 enzymes.PMID 15210869Read ↗

In vivo Phenotyping Methods: Cytochrome P450 Probes with Emphasis on the Cocktail Approach.Semantic proximity Read ↗

Simultaneous Determination of Cytochrome P450 Oxidation Capacity in Humans: A Review on the Phenotyping Cocktail Approach.Semantic proximity Read ↗

Evaluation of drug-metabolizing enzyme hydroxylation phenotypes in Hispanic populations: the CEIBA cocktail.Semantic proximity Read ↗

Strategies and Molecular Probes to Investigate the Role of Cytochrome P450 in Drug MetabolismSemantic proximity Read ↗

Cytochromes P450: decision-making tools for personalized therapeutics.Semantic proximity Read ↗

How useful is the "cocktail approach" for evaluating human hepatic drug metabolizing capacity using cytochrome P450 phenotyping probes in vivo?Semantic proximity Read ↗

Simultaneous in vivo phenotyping of CYP enzymes.Semantic proximity Read ↗

Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism.Semantic proximity Read ↗

Phenotyping of CYP450 in human liver microsomes using the cocktail approach.Semantic proximity Read ↗

Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes.Semantic proximity Read ↗

Multiplex Phenotyping for Systems Medicine: A One-Point Optimized Practical Sampling Strategy for Simultaneous Estimation of CYP1A2, CYP2C9, CYP2C19, and CYP2D6 Activities Using a Cocktail Approach.Semantic proximity Read ↗

Measuring pharmacogenetics in special groups: geriatrics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.