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Article

The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse.

Oncology reports - 1 Jul 2004

Hulboy Diana L, Gautam Shiva, Fingleton Barbara, Matrisian Lynn M

Abstract excerpt

The multiple intestinal neoplasia (Min/+) mouse, which carries a mutant adenomatous polyposis coli (Apc) allele, is a model for human familial colon cancer. Like the human syndrome caused by mutant APC, the Min/+ mouse syndrome shows susceptibility to tumors of other tissues, including the mammary gland. The matrix metalloproteinase (MMP) MMP-7 (matrilysin) gene is transcriptionally induced by signal transduction...

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Source

Identifiers

PMID: 15201952

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse.PMID 15201952Read ↗

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin.Semantic proximity Read ↗

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Smad3 Deficiency Promotes Tumorigenesis in the Distal Colon of ApcMin/+ MiceSemantic proximity Read ↗

Induction of inflammatory bowel disease accelerates adenoma formation in Min +/- mice.Semantic proximity Read ↗

Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway.Semantic proximity Read ↗

Identification of Mom7, a novel modifier of Apc(Min/+) on mouse chromosome 18.Semantic proximity Read ↗

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