Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo.

Genes & development - 1 Jul 2004

Wolff Christian, Roy Sudipto, Lewis Katharine E, Schauerte Heike, Joerg-Rauch Gerd, Kirn Annette, Weiler Christian, Geisler Robert, Haffter Pascal, Ingham Philip W

Abstract excerpt

Signaling by lipid-modified secreted glycoproteins of the Hedgehog family play fundamental roles during pattern formation in animal development and in humans; dysfunction of Hedgehog pathway components is frequently associated with a variety of congenital abnormalities and cancer. Transcriptional regulation of Hedgehog target genes is mediated by members of the Gli zinc-finger transcription factors. The relative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclic AMP-Dependent Protein Kinases
Share to Hedgehog Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oncogene Proteins

Share to Receptors, G-Protein-Coupled

Share to Smoothened Receptor

Share to Zinc Finger Protein GLI1

Share to Zinc Finger Protein Gli2

Share to Zinc Fingers

Source

Open in PubMed Open full text

Identifiers

PMID: 15198976
DOI: 10.1101/gad.296004
PMCID: PMC443519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo.PMID 15198976Read ↗

The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling.Semantic proximity Read ↗

Gli proteins encode context-dependent positive and negative functions: implications for development and diseaseSemantic proximity Read ↗

The Hedgehog Signal Transduction NetworkSemantic proximity Read ↗

Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease.Semantic proximity Read ↗

The hedgehog signaling network.Semantic proximity Read ↗

GLI transcription factors: mediators of oncogenic Hedgehog signalling.Semantic proximity Read ↗

The ZIC gene family encodes multi-functional proteins essential for patterning and morphogenesis.Semantic proximity Read ↗

Grainyhead-like (Grhl) Target Genes in Development and CancerSemantic proximity Read ↗

Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis.Semantic proximity Read ↗

Transcriptional regulation of the Hedgehog effector CI by the zinc-finger gene combgap.Semantic proximity Read ↗

Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif.Semantic proximity Read ↗

Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.