Article
Glutathione S-transferase M1 and T1 null genotype distribution in South Indians.
European journal of clinical pharmacology - 1 Aug 2004
Naveen A T, Adithan C, Padmaja N, Shashindran C H, Abraham B K, Satyanarayanamoorthy K, Anitha P, Gerard N, Krishnamoorthy R
Abstract excerpt
OBJECTIVE: To investigate the distribution of the homozygous null genotypes of GSTM1 and GSTT1 in the South Indian population. METHODS: Five hundred and seventeen unrelated natives of the South Indian states of Tamilnadu and Pondicherry (n=170), Kerala (n=122), Karnataka (n=110) and Andhra Pradesh (n=115) were analyzed for homozygous deletions of GSTM1 and GSTT1. A multiplex polymerase chain reaction method...
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