Article
Genetic polymorphisms of GSTM1 and GSTT1 genes in Delhi and comparison with other Indian and global populations.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Sharma Anita, Pandey Arvind, Sardana Sarita, Sehgal Ashok, Sharma Joginder K
Abstract excerpt
The glutathione S-transferases (GSTs) are involved in the metabolism of many xenobiotics, including an array of environmental carcinogens, pollutants, and drugs. Genetic polymorphisms in these genes may lead to inter- individual variation in susceptibility to various diseases. In the present study, GSTM1 and GSTT1 polymorphisms were analysed using a multiplex polymerase chain reaction in 500 normal individuals...
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