Article
Genetic variation of GSTM1, GSTT1 and GSTP1 genes in a South Indian population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
V Vettriselvi, K Vijayalakshmi, Paul Solomon Fd, P Venkatachalam
Abstract excerpt
The glutathione S transferase (GST) family of enzymes play a vital role in the phase II biotransformation of environmental carcinogens, pollutants, drugs and other xenobiotics. GSTs are polymorphic and the polymorphisms in GST genes have been associated with cancer susceptibility and prognosis. Moreover, distinct ethnic differences have been observed in the type and frequency of GST gene polymorphisms. Hence, the...
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