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Article

PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2.

The Journal of biological chemistry - 13 Aug 2004

Hidaka Sumi, Könecke Vera, Osten Larissa, Witzgall Ralph

Abstract excerpt

Employing a yeast two-hybrid screen with the COOH terminus of polycystin-2, one of the proteins mutated in patients with polycystic kidney disease, we were able to isolate a novel protein that we call PIGEA-14 (polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein with a molecular mass of 14 kDa). Molecular modeling only predicts a coiled-coil motif, but no other functional domains, in...

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Source

Identifiers

PMID: 15194699
DOI: 10.1074/jbc.M314206200

Genes

PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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