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Article

Role of myostatin in metabolism

10 Jun 2004

Abstract excerpt

PURPOSE OF REVIEW: To review papers on myostatin published in 2003 and early 2004. Myostatin is a negative regulator of skeletal muscle mass produced in this tissue. Inactivating mutations of the myostatin gene or interaction of myostatin protein with follistatin and other inhibitory proteins induce a hypermuscular phenotype in cattle and mice; this is assumed to result from inhibition of muscle cell...

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PMID: 15192449
DOI: 10.1097/01.mco.0000134365.99523.7f

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