Article
Analysis of Drosophila proboscipedia mutant alleles.
Genome - 1 Jun 2004
Tayyab I, Hallahan H M, Percival-Smith A
Abstract excerpt
Proboscipedia (PB) is a HOX protein required for adult maxillary palp and proboscis formation. To identify domains of PB important for function, 21 pb point mutant alleles were sequenced. Twelve pb alleles had DNA sequence changes that encode an altered PB protein product. The DNA sequence changes of these 12 alleles fell into 2 categories: missense alleles that effect the PB homeodomain (HD), and nonsense or...
Topics
- Alleles
- Animals
- Base Sequence
- DNA Primers
- Drosophila
- Drosophila Proteins
- Homeodomain Proteins
- Immunoprecipitation
- Models, Molecular
- Mutation, Missense
- Transcription Factors
- Two-Hybrid System Techniques