Article
Ectopic expression of the Drosophila homeotic gene proboscipedia under Antennapedia P1 control causes dominant thoracic defects.
Genetics - 1 Nov 1992
Cribbs D L, Pattatucci A M, Pultz M A, Kaufman T C
Abstract excerpt
A deletion mutation in the Antennapedia Complex of Drosophila melanogaster, Df(3R)SCBXL2, induces both dominant and recessive loss-of-function phenotypes. The deletion is associated with diminished function of proboscipedia (pb), a homeotic gene required for mouthparts formation. Df(3R)SCBXL2 also has associated dominant thoracic defects related to diminished expression of the homeotic Antennapedia (Antp) gene...
Topics
- Animals
- Chromosome Deletion
- Drosophila melanogaster
- Female
- Gene Expression Regulation
- Genes, Dominant
- Genes, Homeobox
- Genes, Recessive
- Male
- Phenotype
- Promoter Regions, Genetic