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Article

Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jun 2004

Willy Patricia J, Murray Ian R, Qian Jing, Busch Brett B, Stevens William C, Martin Richard, Mohan Raju, Zhou Sihong, Ordentlich Peter, Wei Ping, Sapp Douglas W, Horlick Robert A, Heyman Richard A, Schulman Ira G

Abstract excerpt

Peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator 1alpha (PGC-1alpha) is a transcriptional coactivator that is a key component in the regulation of energy production and utilization in metabolic tissues. Recent work has identified PGC-1alpha as a strong coactivator of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha), implicating ERRalpha as a potential mediator of...

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Identifiers

PMID: 15184675
DOI: 10.1073/pnas.0401420101
PMCID: PMC428446

Genes

PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand.PMID 15184675Read ↗

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The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).Semantic proximity Read ↗

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International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.Semantic proximity Read ↗

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