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Article

Distinct Diversity of the cag Pathogenicity Island among Helicobacter pylori Strains in Japan

1 Jun 2004

Abstract excerpt

The severity of Helicobacter pylori-related disease is correlated with the presence of a cag pathogenicity island (PAI). Genetic diversity within the cag PAI may have a modifying effect on the pathogenic potential of the infecting strain. We analyzed the complete cag PAI sequences of 11 representative Japanese strains according to their vacA genotypes and clinical effects and examined the relationship between the...

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PMID: 15184428
DOI: 10.1128/jcm.42.6.2508-2517.2004

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