Article
Correlation between variation of the 3' region of the cagA gene in Helicobacter pylori and disease outcome in Japan.
The Journal of infectious diseases - 1 Dec 2002
Azuma Takeshi, Yamakawa Akiyo, Yamazaki Shiho, Fukuta Kanako, Ohtani Masahiro, Ito Yoshiyuki, Dojo Manabu, Yamazaki Yukinao, Kuriyama Masaru
Abstract excerpt
Genetic diversity within the cag pathogenicity island (PAI) of Helicobacter pylori may have a modifying effect on the pathogenic potential of the infecting strain. The genetic structure of the cag PAI was examined in Japanese isolates. The composition and nucleotide sequences of the cag PAI were...
Topics
- Amino Acid Sequence
- Antigens, Bacterial
- Bacterial Proteins
- Disease Progression
- Female
- Gastritis, Atrophic
- Gastrointestinal Diseases
- Genetic Variation
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Japan
- Male
- Middle Aged
- Molecular Sequence Data