Article
Significant allelic loss of ANX7region (10q21) in hormone receptor negative breast carcinomas.
Cancer letters - 16 Jul 2004
Leighton Ximena, Srikantan Vasanta, Pollard Harvey B, Sukumar Saraswati, Srivastava Meera
Abstract excerpt
Loss of heterozygosity (LOH) in the 10q21 region that harbors the tumor suppressor gene ANX7-GTPase gene have been found in 35% of prostate tumors. Therefore, the rationale for this study is that this gene could also be implicated in breast pathogenesis as well. We investigated allelic losses in microsatellites of the 10q21 region, and their correlations with ANX7 status, estrogen receptor (ER) status,...
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