Article
Drosophila par-1 is required for oocyte differentiation and microtubule organization.
Current biology : CB - 23 Jan 2001
Cox D N, Lu B, Sun T Q, Williams L T, Jan Y N
Abstract excerpt
BACKGROUND: Drosophila oocyte determination involves a complex process by which a single cell within an interconnected cyst of 16 germline cells differentiates into an oocyte. This process requires the asymmetric accumulation of both specific messenger RNAs and proteins within the future oocyte as well as the proper organization of the microtubule cytoskeleton, which together with the fusome provides polarity...
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