Article
Symmetry breaking during Drosophila oogenesis.
Cold Spring Harbor perspectives in biology - 1 Aug 2009
Roth Siegfried, Lynch Jeremy A
Abstract excerpt
The orthogonal axes of Drosophila are established during oogenesis through a hierarchical series of symmetry-breaking steps, most of which can be traced back to asymmetries inherent in the architecture of the ovary. Oogenesis begins with the formation of a germline cyst of 16 cells connected by ring canals. Two of these 16 cells have four ring canals, whereas the others have fewer. The first symmetry-breaking...
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