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Article

Catalytic and structural contributions for glutathione-binding residues in a Delta class glutathione S-transferase.

The Biochemical journal - 1 Sept 2004

Winayanuwattikun Pakorn, Ketterman Albert J

Abstract excerpt

Glutathione S-transferases (GSTs) are dimeric proteins that play a major role in cellular detoxification. The GSTs in mosquito Anopheles dirus species B, an important malaria vector in South East Asia, are of interest because they can play an important role in insecticide resistance. In the present study, we characterized the Anopheles dirus (Ad)GST D3-3 which is an alternatively spliced product of the adgst1AS1...

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Identifiers

PMID: 15182230
DOI: 10.1042/BJ20040697
PMCID: PMC1133834

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