Article
Catalytic and structural contributions for glutathione-binding residues in a Delta class glutathione S-transferase.
The Biochemical journal - 1 Sept 2004
Winayanuwattikun Pakorn, Ketterman Albert J
Abstract excerpt
Glutathione S-transferases (GSTs) are dimeric proteins that play a major role in cellular detoxification. The GSTs in mosquito Anopheles dirus species B, an important malaria vector in South East Asia, are of interest because they can play an important role in insecticide resistance. In the prese...
Topics
- Amino Acid Sequence
- Amino Acids
- Animals
- Anopheles
- Binding Sites
- Catalysis
- Catalytic Domain
- Enzyme Stability
- Glutathione
- Glutathione Transferase
- Hot Temperature
- Insect Proteins
- Kinetics
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Binding
- Protein Folding