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Article

Role of Ser11 in the stabilization of the structure of Ochrobactrum anthropi glutathione transferase.

The Biochemical journal - 15 Apr 2007

Federici Luca, Masulli Michele, Bonivento Daniele, Di Matteo Adele, Gianni Stefano, Favaloro Bartolo, Di Ilio Carmine, Allocati Nerino

Abstract excerpt

GSTs (glutathione transferases) are a multifunctional group of enzymes, widely distributed and involved in cellular detoxification processes. In the xenobiotic-degrading bacterium Ochrobactrum anthropi, GST is overexpressed in the presence of toxic concentrations of aromatic compounds such as 4-chlorophenol and atrazine. We have determined the crystal structure of the GST from O. anthropi (OaGST) in complex with...

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Identifiers

PMID: 17223798
DOI: 10.1042/BJ20061707
PMCID: PMC1874244

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