Article
Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis.
The Journal of biological chemistry - 13 Aug 2004
Jiménez Alberto, Zu Wei, Rawe Vanesa Y, Pelto-Huikko Markku, Flickinger Charles J, Sutovsky Peter, Gustafsson Jan-Ake, Oko Richard, Miranda-Vizuete Antonio
Abstract excerpt
Mammalian germ cells are endowed with a complete set of thioredoxins (Trx), a class of redox proteins located in specific structures of the spermatid and sperm tail. We report here the characterization, under normal and pathological conditions, of a novel thioredoxin with a germ line-restricted expression pattern, named spermatocyte/spermatid-specific thioredoxin-3 (SPTRX-3). The human SPTRX-3 gene maps at 9q32,...
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