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Article

Diagnosis and treatment of medullary thyroid cancer.

Bailliere's best practice & research. Clinical endocrinology & metabolism - 1 Dec 2000

Modigliani E, Franc B, Niccoli-sire P

Abstract excerpt

Medullary carcinoma of the thyroid (MTC) is a rare tumour derived from thyroid C cells with serum calcitonin as a specific and sensitive marker. MTC is inherited in 25% of cases, with an autosomal dominant transmission, age-related penetrance and variable expressivity. MTC is an obligatory component of multiple endocrine neoplasia type 2 (MEN2), which comprises three well defined syndromes: MEN2A, which may be...

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PMID: 11289739
DOI: 10.1053/beem.2000.0107

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