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Medullary thyroid carcinoma and multiple endocrine neoplasia type 2.

Endocrine pathology - 1 Jan 2003

Takami Hiroshi

Abstract excerpt

Medullary thyroid carcinoma (MTC) occurs as both a sporadic and an inherited disease. MTC is a consistent feature of multiple endocrine neoplasia (MEN) 2A, MEN 2B, and familial non-MEN MTC (FMTC). Plasma calcitonin is a sensitive and specific marker for the presence of MTC. Genetic testing can identify mutant gene carriers, and prophylactic total thyroidectomy should be carried out in patients with the mutant...

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PMID: 12858002
DOI: 10.1385/ep:14:2:123

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