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Article

Electrical remodeling and arrhythmias in long-QT syndrome: lessons from genetic models in mice.

Annals of medicine - 1 Jan 2004

Koren Gideon

Abstract excerpt

Mutations in cardiac voltage-gated K+ channels cause long-QT syndrome (LQTS) and sudden death. We have created a mouse with a long-QT phenotype by overexpression of truncated K+ channels in the heart and have investigated the phenotype of these mice. These mice have long-QT phenotype, and spontaneous and inducible arrhythmias. Optical mapping of Kv1DN mice revealed spatial and temporal dispersion of...

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Source

Identifiers

PMID: 15176420
DOI: 10.1080/17431380410032643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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