Electrophysiological phenotyping in genetically engineered mice.

Abstract excerpt

Advances in transgene and gene targeting technology have enabled sophisticated manipulation of the mouse genome, providing important insights into the molecular mechanisms underlying cardiac conduction, arrhythmogenesis, and sudden cardiac death. The mouse is currently the principal mammalian model for studying biological processes, particularly related to cardiac pathophysiology. Murine models have been...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiovascular Diseases
• Share to Disease Models, Animal
• Share to Electrophysiology