Article
Biochemical and functional characterization of the SMC holocomplex from Mycobacterium smegmatis.
Microbiology (Reading, England) - 1 Feb 2021
Pradhan Suchitra, K Shwetha, Kumari Pratibha, Kumar Ravi
Abstract excerpt
Multi-subunit SMC complexes are required to perform essential functions, such as chromosome compaction, segregation and DNA repair, from bacteria to humans. Prokaryotic SMC proteins form complexes with two non-SMC subunits, ScpA and ScpB, to condense the chromosome. The mutants of both scpa and scpb genes in Bacillus subtilis have been shown to display characteristic phenotypes such as growth defects and...
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