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Article

Single nucleotide polymorphism in the low-density lipoprotein receptor is associated with a threefold risk of stroke. A case-control and prospective study.

European heart journal - 1 Jun 2004

Frikke-Schmidt Ruth, Nordestgaard Børge G, Schnohr Peter, Tybjaerg-Hansen Anne

Abstract excerpt

BACKGROUND: More than 600 different, but rare, mutations in the low-density lipoprotein (LDL) receptor have been identified as the cause of familial hypercholesterolaemia. In contrast, only a single common amino acid-changing polymorphism (A370T) has been reported in this gene. The association of this polymorphism with variations in lipid levels is at present unclear. METHODS: We obtained genotypes for 9238...

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Identifiers

PMID: 15172466
DOI: 10.1016/j.ehj.2004.03.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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