Article
Elevated white cell count in acute coronary syndromes: relationship to variants in inflammatory and thrombotic genes.
BMC medical genetics - 1 Jun 2004
Byrne Connie E, Fitzgerald Anthony, Cannon Christopher P, Fitzgerald Desmond J, Shields Denis C
Abstract excerpt
BACKGROUND: Elevated white blood cell counts (WBC) in acute coronary syndromes (ACS) increase the risk of recurrent events, but it is not known if this is exacerbated by pro-inflammatory factors. We sought to identify whether pro-inflammatory genetic variants contributed to alterations in WBC and C-reactive protein (CRP) in an ACS population. METHODS: WBC and genotype of interleukin 6 (IL-6 G-174C) and of...
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