Article
3-T proton MRS investigation of glutamate and glutamine in adolescents at high genetic risk for schizophrenia.
The American journal of psychiatry - 1 Jun 2004
Tibbo Philip, Hanstock Chris, Valiakalayil Agitha, Allen Peter
Abstract excerpt
OBJECTIVE: Glutamate and glutamine were examined in vivo in nonpsychotic adolescents at high genetic risk for schizophrenia by using 3-T proton magnetic resonance spectroscopy ((1)H-MRS). METHOD: Spectra from the right medial frontal lobe of 20 adolescents who had a parent with schizophrenia (high-risk group; mean age=16.4 years) were compared with spectra obtained from adolescent offspring of parents with no...
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