Article
Single amino acid exchanges in separate domains of the Drosophila serendipity delta zinc finger protein cause embryonic and sex biased lethality.
Genetics - 1 Aug 1992
Crozatier M, Kongsuwan K, Ferrer P, Merriam J R, Lengyel J A, Vincent A
Abstract excerpt
The Drosophila serendipity (sry) delta (delta) zinc finger protein is a sequence-specific DNA binding protein, maternally inherited by the embryo and present in nuclei of transcriptionally active cells throughout fly development. We report here the isolation and characterization of four ethyl methanesulfate-induced zygotic lethal mutations of different strengths in the sry delta gene. For the stronger allele, all...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA
- Drosophila
- Female
- Genes, Lethal
- Genetic Complementation Test
- Male
- Molecular Sequence Data