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Article

Frequency distribution of thiopurine S-methyltransferase activity in red blood cells of a healthy Japanese population.

Therapeutic drug monitoring - 1 Jun 2004

Kubota Takahiro, Nishida Akihito, Takeuchi Ken, Iida Takayuki, Yokota Hiromitsu, Higashi Katsumi, Nakahara Kazuhiko, Hanai Hiroyuki, Iga Tatsuji

Abstract excerpt

Thiopurine S-methyltransferase (TPMT), which exhibits a genetic polymorphism, plays an important role in the metabolism of thiopurine drugs such as mercaptopurine, thioguanine, and azathioprine. To determine the frequency distribution of TPMT activity in 157 Japanese subjects with different TPMT...

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Source

Identifiers

PMID: 15167635
DOI: 10.1097/00007691-200406000-00017

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15167635-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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