Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene.

Journal of human genetics - 1 Jan 2000

Seki T, Tanaka T, Nakamura Y

Abstract excerpt

Thiopurine S-methyltransferase (TPMT) catalyzes the S-methylation of drugs such as azathiopurine, 6-mercaptopurine, and 6-thioguanine, which are widely prescribed for immunosuppressive or cytotoxic applications. We report here the entire genomic structure of the TPMT gene and the presence of 30 s...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to TPMT gene
Share to Methyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Polyomavirus and related diseases

Share to Viral-associated cancers and disorders

Source

Identifiers

PMID: 11043513
DOI: 10.1007/s100380070020

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11043513-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene.PMID 11043513Read ↗

Three novel single nucleotide polymorphisms of the human thiopurine S-methyltransferase gene in Japanese individuals.Semantic proximity Read ↗

The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics.Semantic proximity Read ↗

Clinical pharmacogenomics of thiopurine S-methyltransferase.Semantic proximity Read ↗

Genotyping of thiopurine methyltransferase using pyrosequencing.Semantic proximity Read ↗

Recent advances in the pharmacogenomics of thiopurine methyltransferase.Semantic proximity Read ↗

Frequency of thiopurine S-methyltransferase (TPMT) alleles in southeast Iranian population.Semantic proximity Read ↗

Thiopurine methyltransferase (TPMT) genotyping to predict myelosuppression riskSemantic proximity Read ↗

Genetic polymorphism of thiopurine S-methyltransferase: clinical importance and molecular mechanisms.Semantic proximity Read ↗

Genetic analysis of thiopurine methyltransferase polymorphism in a Japanese population.Semantic proximity Read ↗

Clinical utility of thiopurine S-methyltransferase genotyping.Semantic proximity Read ↗

Identification of a novel thiopurine S-methyltransferase allele (TPMT*37).Semantic proximity Read ↗

Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.