Article
Insights into recombination from patterns of linkage disequilibrium in humans.
Genetics - 1 May 2004
Ptak Susan E, Voelpel Kristian, Przeworski Molly
Abstract excerpt
An ability to predict levels of linkage disequilibrium (LD) between linked markers would facilitate the design of association studies and help to distinguish between evolutionary models. Unfortunately, levels of LD depend crucially on the rate of recombination, a parameter that is difficult to measure. In humans, rates of genetic exchange between markers megabases apart can be estimated from a comparison of...
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