Article
Identification of novel dominant INO2c mutants with an Opi- phenotype.
Molecular microbiology - 1 Jun 2004
Gardenour Kyle R, Levy Jamie, Lopes John M
Abstract excerpt
The INO2 gene of Saccharomyces cerevisiae is required for derepression of the phospholipid biosynthetic genes in response to inositol depletion. Conversely, the OPI1 gene is required for repression in response to inositol supplementation. Results of an in vitro assay have led to a model in which Opi1p interacts with Ino2p. However, there is no in vivo evidence to support this model. Additionally, most of the...
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