Article
Pleiotropic effects of the opi1 regulatory mutation of yeast: its effects on growth and on phospholipid and inositol metabolism.
Microbiology (Reading, England) - 1 Oct 1998
Jiranek Vladimir, Graves J Anthony, Henry Susan A
Abstract excerpt
Key factors which impact on the biosynthesis and subsequent fate of the phospholipid precursor inositol were studied as a function of growth phase in the yeast Saccharomyces cerevisiae. Both wild-type and strains disrupted for the OPI1 gene, the principal negative regulator of the phospholipid bi...
Topics
- Blotting, Northern
- Gene Expression Regulation, Fungal
- Inositol
- Mutation
- Myo-Inositol-1-Phosphate Synthase
- Osmotic Pressure
- Phenotype
- Phosphatidic Acids
- Phosphatidylcholines
- Phosphatidylethanolamines
- Phosphatidylinositols