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Article

Functional characterization of genetic polymorphisms identified in the human cytochrome P450 4F12 (CYP4F12) promoter region.

Biochemical pharmacology - 15 Jun 2004

Cauffiez Christelle, Klinzig Florian, Rat Emmanuel, Tournel Gilles, Allorge Delphine, Chevalier Dany, Lovecchio Tonio, Pottier Nicolas, Colombel Jean-Frédéric, Lhermitte Michel, D'Halluin Jean-Claude, Broly Franck, Lo-Guidice Jean-Marc

Abstract excerpt

The human cytochrome CYP4F12 has been shown to be active toward inflammatory mediators and exogenous compounds such as antihistaminic drugs. In the present study, we report the first investigation of polymorphisms in the human CYP4F12 gene. A screening for sequence variations in the 5'-flanking region was performed by a Polymerase Chain Reaction-Single Strand Conformational Polymorphism (PCR-SSCP) strategy, using...

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Identifiers

PMID: 15163554
DOI: 10.1016/j.bcp.2004.02.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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