Article
Ivermectin-facilitated immunity in onchocerciasis. Reversal of lymphocytopenia, cellular anergy and deficient cytokine production after single treatment.
Clinical and experimental immunology - 1 Sept 1992
Soboslay P T, Dreweck C M, Hoffmann W H, Lüder C G, Heuschkel C, Görgen H, Banla M, Schulz-Key H
Abstract excerpt
A longitudinal investigation has been conducted into the cell-mediated immune responses of onchocerciasis patients after a single-dose treatment with ivermectin. Untreated patients tested for delayed cutaneous hypersensitivity (DCH) to seven recall antigens showed lower responses than infection-free control individuals (P less than 0.01), but 6 and 14 months after treatment DCH reactions increased to similar...
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