Article
Onchocerca volvulus provides ligands for the stimulation of human gamma/delta T lymphocytes expressing V delta 1 chains.
The Journal of infectious diseases - 1 Nov 1993
Munk M E, Soboslay P T, Arnoldi J, Brattig N, Schulz-Key H, Kaufmann S H
Abstract excerpt
Peripheral blood mononuclear cells (PBMC) from 8 onchocerciasis patients, treated or not with ivermectin, were analyzed for phenotypic cell surface markers. A significant increase (P < .05) in gamma/delta T cells expressing the V delta 1 chain compared with normal and endemic controls was detecte...
Topics
- Adult
- Animals
- Antigens, Helminth
- CD3 Complex
- Cells, Cultured
- Female
- Flow Cytometry
- Humans
- Immunohistochemistry
- Ligands
- Lymphocyte Activation
- Male
- Onchocerca volvulus
- Onchocerciasis
- Phenotype
- Receptors, Antigen, T-Cell, gamma-delta
- Skin
- T-Lymphocytes