Article
Onchocerca volvulus provides ligands for the stimulation of human gamma/delta T lymphocytes expressing V delta 1 chains.
The Journal of infectious diseases - 1 Nov 1993
Munk M E, Soboslay P T, Arnoldi J, Brattig N, Schulz-Key H, Kaufmann S H
Abstract excerpt
Peripheral blood mononuclear cells (PBMC) from 8 onchocerciasis patients, treated or not with ivermectin, were analyzed for phenotypic cell surface markers. A significant increase (P < .05) in gamma/delta T cells expressing the V delta 1 chain compared with normal and endemic controls was detected in all patients. PBMC populations from onchocerciasis patients were not expanded after restimulation with Onchocerca...
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