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Article

Elevated IL‐10 mRNA expression and downregulation of Th1‐type cytokines in microfilaraemic individuals with <i>Wuchereria bancrofti</i> infection

1 Feb 1997

Abstract excerpt

To understand the molecular basis of parasite-specific anergy in human lymphatic filariasis caused by the nematode Wuchereria bancrofti, parasite antigen-dependent cellular proliferation and cytokine gene expression were investigated. By reverse transcriptase polymerase chain reaction (RT-PCR), the levels of cytokine mRNA were determined in the peripheral blood mononuclear cells (PBMCs) of different clinical...

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PMID: 9076809
DOI: 10.1046/j.1365-3024.1997.d01-185.x

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