Article
Immunoregulation in onchocerciasis. Functional and phenotypic abnormalities of lymphocyte subsets and changes with therapy.
The Journal of clinical investigation - 1 Jul 1991
Freedman D O, Lujan-Trangay A, Steel C, Gonzalez-Peralta C, Nutman T B
Abstract excerpt
To help define the immunoregulatory defects in patients with onchocerciasis, flow cytometric analysis of circulating lymphocyte subpopulations was performed in parallel with functional assays. No significant differences in CD4/CD8 ratios were seen when microfilariae-positive individuals from Guat...
Topics
- Adolescent
- Adult
- Antigens, Differentiation
- CD4 Antigens
- HLA-DR Antigens
- Histocompatibility Antigens
- Humans
- Interleukin-2
- Interleukin-4
- Leukocyte Common Antigens
- Lymphocyte Subsets
- Male
- Middle Aged
- Onchocerciasis
- Phenotype