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Article

A NHERF binding site links the betaPDGFR to the cytoskeleton and regulates cell spreading and migration.

Journal of cell science - 15 Jun 2004

James Marianne F, Beauchamp Roberta L, Manchanda Nitasha, Kazlauskas Andrius, Ramesh Vijaya

Abstract excerpt

The Na(+)/H(+) exchanger regulatory factor, NHERF, is a multifunctional adapter protein involved in a wide range of physiological activities. NHERF associates with merlin and the ezrin/radixin/moesin (MERM) family of membrane-actin cytoskeletal linker proteins through its C-terminus and is capable of interacting via its PDZ1 domain to the betaPDGF receptor (betaPDGFR). Thus, NHERF, potentially links the betaPDGFR...

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Identifiers

PMID: 15161943
DOI: 10.1242/jcs.01156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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