Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of<i>HOX</i>Genes in Acute Leukemia Cell Lines with and without<i>MLL</i>Translocations

30 Dec 2003

Abstract excerpt

In primary cells from acute leukemia patients, expression of the genes MEIS1, HOXA5, HOXA7 and HOXA9 has been reported to be correlated with the occurrence of MLL translocations. It was our aim to find out whether MLL mutant (MLLmu) and MLL wild-type (MLLwt) acute leukemia-derived cell lines might likewise be discriminated on the basis of HOX gene expression. Southern blot analysis, performed to verify the MLL...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer-related gene regulation
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15160920
DOI: 10.1080/10428190310001609942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of<i>HOX</i>Genes in Acute Leukemia Cell Lines with and without<i>MLL</i>TranslocationsPMID 15160920Read ↗

Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia.Semantic proximity Read ↗

Down-regulation of homeobox genes <i>MEIS1</i> and <i>HOXA</i> in <i>MLL</i> -rearranged acute leukemia impairs engraftment and reduces proliferationSemantic proximity Read ↗

HOXA9 is required for survival in human MLL-rearranged acute leukemias.Semantic proximity Read ↗

Gene expression profiling–based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infantsSemantic proximity Read ↗

<i>Hox</i> gene Dysregulation in Acute Myeloid LeukemiaSemantic proximity Read ↗

Chromosomal Rearrangements Leading to MLL Gene Fusions: Clinical and Biological AspectsSemantic proximity Read ↗

A distinct set of long non-coding RNAs in childhood MLL-rearranged acute lymphoblastic leukemia: biology and epigenetic targetSemantic proximity Read ↗

A role for MEIS1 in MLL-fusion gene leukemiaSemantic proximity Read ↗

Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulationSemantic proximity Read ↗

Identification of <i>MLL</i> partner genes in 27 patients with acute leukemia from a single cytogenetic laboratorySemantic proximity Read ↗

Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia.Semantic proximity Read ↗

Deregulation of the HOXA9/MEIS1 axis in acute leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.