Article
Evolution Of Clonal Cytogenetic Abnormalities in Aplastic Anemia
30 Dec 2003
Abstract excerpt
Prior to the introduction of effective therapies, the high mortality rates of severe aplastic anemia (AA) precluded recognition of late complications of this disease. Once the survival of AA improved, observation of clonal evolution raised questions as to whether the development of secondary myelodysplastic syndrome (MDS) is a part of the extended natural history of the disease or is related to the therapies...
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